Welcome

Our research focuses on unraveling the implications of distinct epigenetic factors on chromatin structure and gene regulation. We aim to understand the underlying molecular mechanisms which result in dynamic changes of the epigenome and are key to cellular identity and functions during development and disease.

To this end, we are utilizing next- and third generation sequencing technologies and develop novel laboratory, as well as computational tools to study epigenetic modifications on single molecule level.

By decoding epigenetic pathways on a molecular level, our goal is to provide the basis for novel therapeutic approaches, as well as new strategies for cell (re)programming and (trans)differentiation.